Seven Hills Bioreagents - Anti-SP-B

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Dong M et al.
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol. Biol. Cell 2008;19:2620-2630.

Stahlman MT et al.
Expression of ABCA3 in developing lung and other tissues. J Histochem Cytochem 2007;55:71-83.

Anti-SP-B - Rabbit

Price:	$ 260.00

Surfactant protein B (SP-B) is expressed alveolar Type II cells in human and mouse. SP-B enhances the spreading and stability of surfactant phospholipids in the alveolus.

Details:

Download datasheet

Catalog Number	WRAB-SPB
Quantity	100 µl
Price	$260.00
Category	Polyclonal
Specificity	human, mouse, cow & sheep SP-B, other species not tested
Immunogen	purified human SP-B
Isotype	N/A
Applications & suggested dilutions	Immunoblots - 1:5000 (reduced/non-reduced samples) ELISA - 1:500-1:1000 Immunohistochemistry - 1:1000
Supplied As	Rabbit serum containing 0.01% sodium azide.
Storage	Aliquot and store at -20^oC. Multiple freeze/thaw cycles not recommended.

References:

Clark JC, Wert SE, Bachurski CJ, Stahlman MT, Stripp BR, Weaver TE, Whitsett JA. 'Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.' Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7794-8.

Gregory TJ, Longmore WJ, Moxley MA, Whitsett JA, Reed CR, Fowler AA 3rd, Hudson LD, Maunder RJ, Crim C, Hyers TM. 'Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.' J Clin Invest. 1991 Dec;88(6):1976-81.

Nogee LM, Wert SE, Proffit SA, Hull WM, Whitsett JA. 'Allelic heterogeneity in hereditary surfactant protein B (SP-B) deficiency.' Am J Respir Crit Care Med. 2000 Mar;161(3 Pt 1):973-81.

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