Seven Hills Bioreagents - Anti-TTF1

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Dong M et al.
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol. Biol. Cell 2008;19:2620-2630.

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Anti-TTF1 - Rabbit

Price:	$ 175.00

TTF-1 is expressed in airway epithelial cells during lung morphogenesis. This is a newly available rabbit antiserum that works well in immunohistochemistry.

Details:

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Catalog Number	WRAB-TTF1
Quantity	100 µl
Price	$175.00
Category	Polyclonal
Specificity	human & mouse TTF-1, other species not tested
Immunogen	recombinant rat TTF-1 6his fusion
Isotype	N/A
Applications & suggested dilutions	Immunoblots - 1:5000 Immunohistochemistry - 1:1000 to 1:2000 Antigen retrieval: required (see IHC protocol) Blocking condition: 6% block (see IHC protocol)
Supplied As	Rabbit serum containing 0.01% sodium azide.
Storage	Store at -20^oC. Multiple freeze/thaw cycles not recommended.

References:

Zhou L, Lim L, Costa RH, Whitsett JA. 'Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung.' J Histochem Cytochem. 1996 Oct;44(10):1183-93.

Stahlman MT, Gray ME, Whitsett JA. 'Expression of thyroid transcription factor-1(TTF-1) in fetal and neonatal human lung.' J Histochem Cytochem. 1996 Jul;44(7):673-8.

Khoor A, Whitsett JA, Stahlman MT, Olson SJ, Cagle PT. 'Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma.' Hum Pathol. 1999 Jun;30(6):695-700.

deFelice M, Silberschmidt D, DiLauro R, Xu Y, Wert SE, Weaver TE, Bachurski CJ, Clark JC, Whitsett JA. 'TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression.' J Biol Chem. 2003 Sep 12;278(37):35574-83.

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