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Dong M et al.
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol. Biol. Cell 2008;19:2620-2630.

Stahlman MT et al.
Expression of ABCA3 in developing lung and other tissues. J Histochem Cytochem 2007;55:71-83.
Ad5-CMV-activated calcineurin
Price:
$ 450.00
 
Activated calcineurin (amino acids 1-398)
Details:

   Download datasheet

Catalog Number JMAd-03
Quantity 0.5 ml
Price $450.00
Category Calcineurin/NFAT
Gene Activated calcineurin (amino acids 1-398)
Vector Construction Mouse cDNA for truncated CnA-beta was cloned into the multiple cloning site of pAC-CMV-pLpA. The resulting plasmid was cotransfected into HEK293 cells with plasmid pJM17 which contains the Ad5 genome. Homologous recombination between the two plasmids resulted in the replacement of the Ad5 early region 1 with the mouse cDNA for truncated CnA-beta expression cassette, generating a replication deficient recombinant virus.
Supplied As Crude HEK293 cell lysate.
Storage Store at -80oC. Multiple freeze/thaw cycles not recommended.
Epitope Tag None
QC Testing Western Blot
Titer Approx 1E8/ml

References:

Taigen T. De Windt LJ, Lim HW, Molkentin JD. Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. USA. 97:1196-1201.2000.

Recombinant adenovirus was generated as described in Gomez-Foix, AM, et al., J. Biol. Chem. (1992) 267:25129-25134.

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