SOX2 is expressed in the epithelial cells lining the conducting airways during development and in adult lung.
SpecificityMouse, human SOX2
ImmunogenMouse SOX2 peptide (KLH-conjugated)
- Lung Associated Antibodies
& suggested dilutionsImmunoblots - 1:8000
Immunohistochemistry - 1:2000
Supplied AsRabbit serum containing 0.01% sodium azide.
StorageAliquot and store at -20°C. Multiple freeze/thaw cycles not recommended.
Tompkins, DH, Besnard, V, Lange, AW, Wert, SE, Keiser, AR, Smith, AN, Lang, R, Whitsett, JA. Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS One. 2009 Dec 14;4(12):e8248.
Tompkins, DH, Besnard, V, Lange, AW, Keiser, AR, Wert, SE, Bruno, MD, Whitsett, JA. Sox2 Activates Cell Proliferation and Differentiation in the Respiratory Epithelium. Am J Respir Cell Mol Biol. 2010 Sep 20. [Epub ahead of print]