SP-D is a widely distributed member of the "collectin" family of polypeptides secreted onto luminal surfaces by epithelial cells lining ducts of many organs, where it likely plays a role in innate host defense.
Specificity human, mouse, rat SP-D (lung surfactant protein D)
Immunogenpurified mouse SP-D
- Lung Associated Antibodies
& suggested dilutionsImmunoblots - 1:5000, Do not use for immunohistochemistry.
Supplied AsAscites fluid containing 0.01% sodium azide, shipped lyophilized.
Storage After resuspension using deionized water or PBS, store at -20°C.
Wert SE, Yoshida M, LeVine AM, Ikegami M, Jones T, Ross GF, Fisher JH, Korfhagen TR, Whitsett JA. 'Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice'. Proc Natl Acad Sci U S A. 2000 May 23;97(11):5972-7.
Stahlman MT, Gray ME, Hull WM, Whitsett JA. 'Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues.' J Histochem Cytochem. 2002 May;50(5):651-60.
McCormack FX, Whitsett JA. 'The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung.' J Clin Invest. 2002 Mar;109(6):707-12. Review. No abstract available.